11/10/2023 0 Comments My feet itch and burn![]() Sorafenib (Nexavar) and sunitinib (Sutent). Red, painful, numb, or tingling hands and feet Increased, curly, or coarse hair on face and eyelashes These drugs may be prescribed for colorectal cancer, head and neck cancer, lung cancer, and pancreatic cancer. Common skin-related side effects of specific targeted drugsīelow is a list of common targeted therapy drugs that can cause skin related problems.Īfatinib (Gilotrif), cetuximab (Erbitux), erlotinib (Tarceva), gefitinib (Iressa), osimertinib (Tagrisso), and panitumumab (Vectibix). It is important to note that the skin side effects linked with these drugs are not allergic reactions or infections. Managing these side effects can also help avoid major changes to your skin, hair, and nails. Your health care team can help you manage these side effects so treatment can continue. When these drugs affect the blood vessels in the hands and feet, they can cause skin problems. This group of drugs may also be called angiogenesis inhibitors because they block the formation of blood vessels. This protein helps make new blood vessels. Another type of targeted therapy that may cause skin problems includes drugs that block a protein called vascular endothelial growth factor (VEGF). Inflammation around the nails can make grooming, dressing, and other activities painful or difficult.ĭrugs that target VEGF. These openings make the skin more prone to infections. A lot of scratching can result in breaks in the skin. Skin may also become more sensitive to sunlight. The skin can also become very dry and itchy, interfering with daily activities and sleep. But some people have severe rashes that cause major physical and cosmetic discomfort. After several days, pimples and pus bumps appear, and the surrounding skin feels slightly tender. You may notice redness or a warm sensation like a sunburn before the rash begins. It usually happens within the first few weeks of taking these medications. Most people taking drugs that target EGFR develop a rash on their face and upper body. ![]() This means rashes and changes to the hair and nails may occur during treatment with these drugs. It also plays a role in the normal growth of the skin, hair, and nails. This common type of targeted therapy focuses on a molecule known as epidermal growth factor receptor (EGFR). If your doctor prescribes a targeted therapy, ask what side effects to expect and how they will be treated.ĭrugs that target EGFR. The following are some of the types of targeted therapies that may affect the skin. Targeted therapies that may cause skin problems These side effects are caused by the effect of medications on the healthy growth of these tissues. Some targeted therapies can cause specific side effects to the skin, hair, and nails. Targeted therapy is a treatment that targets the specific genes, proteins, or the tissue environment that contributes to cancer growth and development. This type of care is called palliative care or supportive care. Managing skin reactions and other cancer side effects is an important part of your medical care and treatment. This includes any new symptoms or a change in symptoms. Let your health care team know about any symptoms you experience. This information explains changes to the skin, included related changes to hair, nails, and eyes, that can happen during treatment with targeted therapy or immunotherapy. There are some similarities and differences in side effects between these types of cancer medications compared to chemotherapy drugs. Like other cancer treatments, they often cause side effects. Targeted therapy and immunotherapy are specific types of cancer medications. This content was last updated 1 November 2021.
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